Medicine

Accelerating ASO treatments from advancement to execution

.Completing passions.R.S., M.S., H.G. as well as A.A.R. are actually coordinators of the 1M1M effort. H.G. as well as A.A.R. are actually board of directors participants as well as R.S., M.S. and A.A.R. are members of the scientific advisory committee of N1C. A.A.R. discloses job by LUMC, which possesses patents on exon-skipping technology, a few of which has been accredited to BioMarin and also consequently sublicensed to Sarepta. As co-inventor of some of these patents, A.A.R. was actually qualified to a share of royalties. A.A.R. even more discloses serving as ad hoc professional for PTC Rehabs, Sarepta Rehabs, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Over the last 5 years, A.A.R. also executed ad hoc speaking to for Alpha Anomeric. A.A.R. also reports membership of the clinical boards of advisers of Eisai, Hybridize Therapies, Silence Therapeutics, Sarepta Therapies, Sapreme and also Mitorx. Over the last 5 years, A.A.R. was actually additionally a scientific board of advisers participant for ProQR. Pay for A.A.R. u00e2 s consulting as well as urging tasks is actually paid for to LUMC. Over the last 5 years, LUMC additionally obtained speaker gratuity from PTC Therapeutics, Alnylam Netherlands, Italfarmaco and Pfizer as well as funding for agreement analysis coming from Sapreme, Eisai, Galapagos, Synaffix as well as Alpha Anomeric. Task backing is actually received coming from Sarepta Therapies and Entrada using unrestricted grants. H.G. possesses nothing at all to reveal relative to the topics covered within this document. Before 5 years, he has also received working as a consultant honoraria coming from UCB. M.S. got working as a consultant honoraria from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and Solaxa in the past 5 years, all unconnected to the present document. R.S. possesses absolutely nothing to reveal in regard to the topics dealt with within this composition. She has gotten speaker and/or working as a consultant gratuity or financing additions from Abbvie, Bial, STADA and Everpharma over the last 5 years.